New quantitative phase imaging modalities on standard microscope platforms

Quantitative phase imaging;Image processing

Jenkins, Micah Hamilton ; Gaylord, Thomas K. Electrical and Computer Engineering Chang, Gee-Kung First, Phillip Tibuleac, Sorin Buck, John A. Davis, Don D. ; Gaylord, Thomas K.

University:Georgia Institute of Technology

Department:Electrical and Computer Engineering

关键词: Quantitative phase imaging;    Image processing;   

Others  :  https://smartech.gatech.edu/bitstream/1853/54239/1/JENKINS-DISSERTATION-2015.pdf

美国|英语

来源: SMARTech Repository

【 摘 要 】

Three new reconstruction methods for quantitative phase imaging, including two interrelated two-dimensional methods, called multifilter phase imaging with partially coherent light and phase optical transfer function recovery, which lead to a third three-dimensional method, called tomographic deconvolution phase microscopy, were developed in response to a growing need among biomedical end users for solutions which can be integrated on standard microscope platforms. The performance of these new methods were evaluated using modelling and simulation as well as experimentation with known test cases. In addition to the development of new methods, existing methods for quantitative phase imaging were applied to characterize the effects of manufacturing, cleaving, and fusion splicing in large-mode-area erbium- and ytterbium-doped optical fibers.