Three-dimensional graphene/graphite structure for ultra-sensitive biosensor

Graphene;Bio-sensing;Field Effect Transistor (FET)

Choi, Jonghyun ; Nam ; SungWoo

关键词: Graphene;    Bio-sensing;    Field Effect Transistor (FET);   

Others  :  https://www.ideals.illinois.edu/bitstream/handle/2142/50491/Jonghyun_Choi.pdf?sequence=1&isAllowed=y

美国|英语

来源: The Illinois Digital Environment for Access to Learning and Scholarship

【 摘 要 】

Graphene has been attracting significant research interests for post-silicon electronics due to its unique properties such as extraordinarily high carrier mobility, mechanical robustness/flexibility and biocompatibility. Furthermore, bio-sensing capabilities of graphene-based field-effect transistors interfaced with cells/tissues have been widely investigated by several research groups. However, the reported sensor devices based on graphene have been planar structures, which present substantial challenges for three dimensional (3D) intimate interfacing with biological systems and simultaneous extra- and intracellular sensing of action potentials. Here, a novel approach of graphene transfer is reported to provide intimate and conformal interfacing of biological systems with underlying sensing platforms. Polydimethylsiloxane (PDMS), which is widely accepted as biocompatible material, was used as the substrate material. Toluene was exploited to pre-swell the substrate before the transfer, to reduce the suspension of graphene and consequentially minimize the damage of graphene. The large area, conformal transfer of graphene was characterized with Raman spectroscopy and scanning electron microscope (SEM), demonstrating that the continuous monolayer graphene was on top of 3D features without significant damages. Furthermore, we expand our discussion to the fabrication of graphene-based field-effect sensors and 3D heterostructure consisting of graphene/graphite foams.