Treatment Response in Depression: Predictors and Moderators of Outcome

treatment response;depression;Psychology;Social Sciences;Psychology

Cardinale, RyanLopez-Duran, Nestor L ;

University of Michigan

关键词: treatment response;    depression;    Psychology;    Social Sciences;    Psychology;   

Others  :  https://deepblue.lib.umich.edu/bitstream/handle/2027.42/147538/rcardina_1.pdf?sequence=1&isAllowed=y

瑞士|英语

来源: The Illinois Digital Environment for Access to Learning and Scholarship

【 摘 要 】

Major Depressive Disorder (MDD) is a highly prevalent psychological disorder that affects an estimated 20.6% of adults in the United States. Despite significant research efforts, treatment response rates remain unacceptably low. The Establishing Moderators and Biosignatures of Antidepressant Response for Clinical Care for Depression (EMBARC) study aimed to address this problem through the search for ;;biosignatures;; that include clinical, contextual, and biological measures to identify a more personalized approach to identifying appropriate treatment recommendations. Through three distinct investigations, this dissertation aims to utilize prior research to study ;;biosignatures;; that may be relevant for predicting antidepressant treatment response. Results from this dissertation may inform future personalized approaches to depression care that may reduce the time to receiving adequate treatment.