Guinea-Bissau is fighting a battleagainst poverty, low growth, and political fragility. Eachof these areas presents both a formidable challenge as wellas an opportunity for serious, long-lasting and much-neededchange. Poverty is entrenched, inequality is high and otherhuman development outcomes are weak with many of the keyindicators worsening over time. Fragility is intrinsicallylinked to low growth and lack of inclusiveness. Nonetheless,the country has potential for unlocking income-generatingopportunities for growth. The diagnostics framework of thisSystematic Country Diagnostic (SCD) is based on threeinterrelated themes: (i) inclusiveness of growth; (ii)overall economic growth and macro context; and (iii)sustainability risks, including the overarching issue of fragility.