African Programme for Onchocerciasis Control 1995– 2015 : Updated Health Impact Estimates Based on New Disability Weights

Coffeng, Luc E. ; Stolk, Wilma A. ; Zoure, Honorat G. M. ; Veerman, J. Lennert ; Agblewonu, Koffi B.

Public Library of Science

关键词: river blindness;    onchocerciasis;    Global Burden of Disease;    GBD;   

DOI  :  10.1371/journal.pntd.0002759
RP-ID  :  102429

学科分类：社会科学、人文和艺术（综合）

来源: World Bank Open Knowledge Repository

【 摘 要 】

Since 1995, the African Programme for Onchocerciasis Control (APOC) has coordinated mass treatment with ivermectin in 16 sub-Saharan countries (Angola, Burundi, Cameroon, Central African Republic, Chad, Congo, Democratic Republic of Congo, Equatorial Guinea, Ethiopia, Liberia, Malawi, Nigeria, North Sudan, South Sudan, Uganda, and the United Republic of Tanzania) with the aim to control morbidity due to infection with Onchocerca volvulus, a filarial nematode. Recently, we predicted trends in prevalence of infection, visual impairment, blindness, and troublesome itch due to onchocerciasis in APOC countries for the period 1995–2015, based on extensive data on pre-control infection levels, population coverage of ivermectin mass treatment, and the association between infection and morbidity. We also estimated the associated health impact, expressed in disability-adjusted life years (DALYs).