This Annual Report summarizes and highlights waste generation, waste reduction, pollution prevention accomplishments, and cost avoidance for 44 U.S. Department of Energy reporting sites for Calendar Year 1999. This section summarizes Calendar Year 1999 Complex-wide waste generation and pollution prevention accomplishments. In May 1996, the Secretary of Energy established a 50 percent Complex-Wide Waste Reduction Goal (relative to the 1993 baseline) for routine operations radioactive, mixed, and hazardous waste generation, to the achieved by December 31, 1999. This Report completes the Calendar Year 1993 through 1999 Secretarial Goal period, and documents DOE's performance in relation to the Goals. New pollution prevention and energy efficiency goals for Fiscal Year 2000 through 2010 were issued by Secretary of Energy Bill Richardson in November 1999, and these new goals are briefly introduced in this Report.