Molecular Engineering of Technetium and Rhenium Based Radiopharmaceuticals.

Technical Information Center Oak Ridge Tennessee

关键词: Radiopharmaceuticals;    Rhenium;    Technetium;    Nuclear medicine;    Chemistry;   

RP-ID  :  DE2005823848

学科分类：工程和技术（综合）

美国|英语

来源: National Technical Reports Library

【 摘 要 】

The research was based on the observation that despite the extraordinarily rich coordination chemistry of technetium and rhenium and several notable successes in reagent design, the extensive investigations by numerous research groups on a variety of N(sub 2)S(sub 2) and N(sub 3)S donor type ligands and on HYNIC have revealed that the chemistries of these ligands with Tc and Re are rather complex, giving rise to considerable difficulties in the development of reliable procedures for the development of radiopharmaceutical reagents.