Molecular Engineering of Technetium and Rhenium Based Radiopharmaceuticals

Zubieta, J.

Syracuse University (United States)

关键词: Radiopharmaceuticals;    Rhenium;    62 Radiology And Nuclear Medicine;    Technetium;    Design;   

DOI  :  10.2172/823848
RP-ID  :  None
RP-ID  :  FG02-99ER62791
RP-ID  :  823848

美国|英语

来源: UNT Digital Library

【 摘 要 】

The research was based on the observation that despite the extraordinarily rich coordination chemistry of technetium and rhenium and several notable successes in reagent design, the extensive investigations by numerous research groups on a variety of N{sub 2}S{sub 2} and N{sub 3}S donor type ligands and on HYNIC have revealed that the chemistries of these ligands with Tc and Re are rather complex, giving rise to considerable difficulties in the development of reliable procedures for the development of radiopharmaceutical reagents.