The Pacific Northwest National Laboratory (PNNL) operates a number of research and development facilities for the U.S. Department of Energy (DOE) in the Hanford Site's 300 Area. The liquid wastes from these facilities are discharged to five liquid effluent systems: the Sanitary Waste System (SNS), the Process Sewer (PS), the Retention Process Sewer (RPS), the 325 Radioactive Liquid Waste System (RLWS), and the 331 Aquaculture System. The wastewater from the PS and RPS systems is treated by the 300 Area Treated Effluent Disposal Facility (TEDF) and discharged to the Columbia River via a National Pollutant Discharge Elimination System-permitted outfall. The SNS discharges to the City of Richland Publicly Owned Treatment Works under a contract with the DOE. The RLWS wastewater is transported to tanks in the 200 Area. The aquaculture system discharges water from fish rearing activities to the Columbia River via an NPDES-exempt outfall. The SNS, RLWS, and aquaculture system do not interface with the 300 Area TEDF. The following data are provided in this report for each facility involved: Identification of individual waste streams and an estimate of flow in appropriate units. For intermittent sources, estimates of the weekly flow are acceptable. Identification of constituents present in each individual waste stream; the maximum contaminant concentration for the constituent. The source of the information, either process knowledge or characterization sampling. Description of engineering controls in place to ensure compliance with the Waste Acceptance Criteria. A summation of flows and individual contaminant concentrations. Rationale for connections to the RPS and type of equipment or process served.