GeneLab: Omics Database for Spaceflight Experiments

Ray, Shayoni [Point of Contact] ; Gebre, Samrawit ; Fogle, Homer ; Berrios, Daniel C ; Tran, Peter B ; Galazka, Jonathan M ; Costes, Sylvain V

关键词: DATA BASES;    DATA PRODUCTS;    DATA SYSTEMS;    INFORMATION RETRIEVAL;    METADATA;    MOLECULAR BIOLOGY;    SPACE STATIONS;    SPACEBORNE EXPERIMENTS;   

RP-ID  :  ARC-E-DAA-TN62201

学科分类：社会科学、人文和艺术（综合）

美国|英语

来源: NASA Technical Reports Server

【 摘 要 】

Motivation - To curate and organize expensive spaceflight experiments conducted aboard space stations and maximize the scientific return of investment, while democratizing access to vast amounts of spaceflight related omics data generated from several model organisms. Results - The GeneLab Data System (GLDS) is an open access database containing fully coordinated and curated “omics” (genomics, transcriptomics, proteomics, metabolomics) data, detailed metadata and radiation dosimetry for a variety of model organisms. GLDS is supported by an integrated data system allowing federated search across several public bioinformatics repositories. Archived datasets can be queried using full-text search (e.g., keywords, Boolean and wildcards) and results can be sorted in multifactorial manner using assistive filters. GLDS also provides a collaborative platform built on GenomeSpace for sharing files and analyses with collaborators. It currently houses 172 datasets and supports standard guidelines for submission of datasets, MIAME (for microarray), ENCODE Consortium Guidelines (for RNA-seq) and MIAPE Guidelines (for proteomics).