The interfacial bioscience grand challenge.

Lane, Pamela ; Stevens, Mark Jackson ; Jacobsen, Richard B. ; Hong, Joohee ; Ayson, Marites J. ; Crozier, Paul Stewart ; Wood, Nichole L. ; Schoeniger, Joseph S. ; Kruppa, Gary Hermann ; Sale, Kenneth L. ; Young, Malin M. ; Faulon, Jean-Loup Michel ; Burns, Alan Richard ; Evans, Kervin O. ; Novak, Petr

Sandia National Laboratories

关键词: Protein Structure;    Simulation Protein Structure;    Membrane Proteins;    Cross-Linking;    59 Basic Biological Sciences;   

DOI  :  10.2172/921141
RP-ID  :  SAND2004-8079
RP-ID  :  AC04-94AL85000
RP-ID  :  921141

美国|英语

来源: UNT Digital Library

【 摘 要 】

This report is broken down into the following 3 sections: (1) Chemical Cross-linking and Mass Spectrometry Applied to Determination of Protein Structure and Dynamics; (2) Computational Modeling of Membrane Protein Structure and Dynamics; and (3) Studies of Toxin-Membrane Interactions using Single Molecule Biophysical Methods.