Improved Radiation Dosimetry/Risk Estimates to Facilitate Environmental Management of Plutonium Contaminated Sites

Scott, Bobby R. ; Cheng, Yung-Sung ; Zhou, Yue ; Tokarskaya, Zoya B. ; Zhuntova, Galina V.

Lovelace Biomedical and Environmental Research Institute, Albuquerque, NM (United States)

关键词: Management;    Aerosols;    Lungs;    Chromosomal Aberrations;    Dosimetry;   

DOI  :  10.2172/834691
RP-ID  :  EMSP-73942-2002
RP-ID  :  FG07-00ER62511
RP-ID  :  834691

美国|英语

来源: UNT Digital Library

【 摘 要 】

Our phase-II research relates to evaluating health risks associated with inhaled plutonium (Pu). Our current research objectives are as follows: (1) to extend our stochastic model for deposition of plutonium (Pu) in the respiratory tract to include additional key variability and uncertainty; (2) to generate and analyze risk distributions for deterministic effects in the lung from inhaled Pu that reflect risk model uncertainty; (3) to acquire an improved understanding of key physiological effects of inhaled Pu, based on evaluations of clinical data (e.g., hematological, respiratory function, chromosomal aberrations in lymphocytes) for Mayak workers in Russia that inhaled Pu- 239; (4) to develop biological dosimetry for Pu-239 that was inhaled by some Mayak workers (with unknown intake) based on clinical data for other workers with known Pu-239 intake; (5) to critically evaluate the validity of the linear no-threshold (LNT) risk model as it relates to cancer risks from inhaled Pu-239 (based on Mayak worker data); (6) to evaluate respirator filter penetration frequencies for airborne Pu aerosols using surrogate high density metals.