Analysis of Zolpidem in Postmortem Fluids and Tissues Using Ultra-Performance Liquid Chromatography-Mass Spectrometry

Thompson KS, Lewis RJ, Ritter RM

FAA Office of Aerospace Medicine - Civil Aerospace Medical Institute

关键词: Forensic Toxicology;    Zolpidem;    Ambien;    Postmortem Distribution;    LC/MS/MS;    UPLC;   

RP-ID  :  DOT/FAA/AM-14/4

美国|英语

来源: Federal Aviation Administration

【 摘 要 】

Zolpidem is a nonbenzodiazepine sedative hypnotic drug used for the short-term treatment of insomnia. Its use is common and wide-spread. While quite effective in producing sedation, zolpidem has potentially hazardous side effects when put in the context of complex tasks. Side effects include drowsiness, dizziness, amnesia, nausea, double vision, diminished reflexes, and a lack of coordination.