Existing enterprise information technology (IT) systems often inhibit business flexibility, sometimes with dire consequences. In this position paper, I argue that operating system research should be measured, among other things, against our ability to improve the speed at which businesses can change. I describe some of the ways in which businesses need to change rapidly, speculate about why existing IT infrastructures inhibit useful change, and suggest some relevant OS research problems. Notes: This paper was originally published in the Proceedings of the Tenth Workshop on Hot Topics in Operating Systems (HotOS-X), Santa Fe, NM, June 2005. 11 Pages