New Cyclotron Targetry to Enhance F-18 clinical Position Emission Tomography

J. Michael Doster

关键词: BEAM CURRENTS;    CAPACITY;    CYCLOTRONS;    FLUORINE 18;    POSITRONS;    PRODUCTION;    REMOVAL;    TARGETS;    TOMOGRAPHY;   

DOI  :  10.2172/945375
RP-ID  :  DOE/ID/14593
PID  :  OSTI ID: 945375
Others  :  TRN: US0900876

学科分类：核物理和高能物理

美国|英语

来源: SciTech Connect

【 摘 要 】

This project proposes to develop cyclotron targets that produce F-18 for clinical Positron Emission Tomography (PET) at significantly higher rates than that available from current targetry. This production rate of 18F is directly proportional to the beam current. Higher beam currents would result in increased 18F production but would be accompanied by higher heat loads to the target. The beam power available in most commercial cyclotrons exceeds the heat removal capacity of current target technology by a factor of two to four, significantly limiting the production rate of Fluorine-18.