Development and validation of a kinematically-driven discrete element model of the patellofemoral joint

JOURNAL OF BIOMECHANICS

卷:88

Article

Gustafson, Jonathan A.¹  Elias, John J.²  Debski, Richard E.³  Farrokhi, Shawn⁴ 

[1] Rush Univ, Med Ctr, Dept Orthoped Surg, Chicago, IL 60612 USA

[2] Cleveland Clin Akron Gen, Dept Res, Akron, OH USA

[3] Univ Pittsburgh, Dept Bioengn, Pittsburgh, PA USA

[4] Naval Med Ctr San Diego, DOD VA Extrem Trauma & Amputat Ctr Excellence, San Diego, CA USA

关键词: Patellofemoral;    Discrete element analysis;    Joint contact;    Modeling;    Stress;   

DOI  :  10.1016/j.jbiomech.2019.03.032

来源: Elsevier

【 摘 要 】

Quantifying the complex loads at the patellofemoral joint (PFJ) is vital to understanding the development of PFJ pain and osteoarthritis. Discrete element analysis (DEA) is a computationally efficient method to estimate cartilage contact stresses with potential application at the PFJ to better understand PFJ mechanics. The current study validated a DEA modeling framework driven by PFJ kinematics to predict experimentally-measured PFJ contact stress distributions. Two cadaveric knee specimens underwent quadriceps muscle [215 NI and joint compression [350 N] forces at ten discrete knee positions representing PFJ positions during early gait while measured PFJ kinematics were used to drive specimen-specific DEA models. DEA-computed contact stress and area were compared to experimentally-measured data. There was good agreement between computed and measured mean and peak stress across the specimens and positions (r = 0.63-0.85). DEA-computed mean stress was within an average of 12% (range: 1-47%) of the experimentally-measured mean stress while DEA-computed peak stress was within an average of 22% (range: 1-40%). Stress magnitudes were within the ranges measured (0.17-1.26 MPa computationally vs 0.12-1.13 MPa experimentally). DEA-computed areas overestimated measured areas (average error = 60%; range: 4-117%) with magnitudes ranging from 139 to 307 mm(2) computationally vs 74-194 mm(2) experimentally. DEA estimates of the ratio of lateral to medial patellofemoral stress distribution predicted the experimental data well (mean error = 15%) with minimal measurement bias. These results indicate that kinematically-driven DEA models can provide good estimates of relative changes in PFJ contact stress. (C) 2019 Elsevier Ltd. All rights reserved.

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