Lipid membranes supported on optically transparent nanosilicas: Synthesis and application in characterization of protein-membrane interactions

JOURNAL OF COLLOID AND INTERFACE SCIENCE

卷:355

Article

Fadeev, Alexander Y.¹  DeGrado, William F.² 

[1] Seton Hall Univ, Dept Chem & Biochem, S Orange, NJ 07079 USA

[2] Univ Penn, Dept Biochem & Biophys, Philadelphia, PA 19104 USA

关键词: Lipid membrane;    Silica nanoparticles;    Protein-membrane interactions;   

DOI  :  10.1016/j.jcis.2010.11.064

来源: Elsevier

【 摘 要 】

We describe methods of preparation of lipid membranes supported on optically transparent nanosilicas (20 and 30 nm diameter) and an initial application of these materials to characterize membrane-protein binding using conventional circular dichroism and fluorescence spectroscopy. (C) 2010 Elsevier Inc. All rights reserved.

【 授权许可】

Free