Transvaginal PVDF-mesh for cystocele repair: A cohort study

INTERNATIONAL JOURNAL OF SURGERY

卷:39

Article

Barski, Dimitri¹  Arndt, Christian¹  Gerullis, Holger²  Yang, Jin³  Boros, Mihaly⁴  Otto, Thomas¹  Kolberg, Hans-Christian⁵ 

[1] Lukas Hosp, Dept Urol, Preussenstr 84, D-41464 Neuss, Germany

[2] Carl von Ossietzky Univ Oldenburg, Sch Med & Hlth Sci, Klinikum Oldenburg, Univ Hosp Urol, Oldenburg, Germany

[3] Chengdu Univ, Affiliated Hosp, Dept Urol, Chengdu, Peoples R China

[4] Univ Szeged, Dept Expt Surg, Szeged, Hungary

[5] Marienhosp Bottrop, Dept Gynecol, Bottrop, Germany

关键词: Anterior mesh;    Alloplastic material;    Biocompatibility;    Vaginal wall prolapse;    Cystocele;    IDEAL;   

DOI  :  10.1016/j.ijsu.2017.02.006

来源: Elsevier

【 摘 要 】

Introduction: Optimized biocompatibility of new materials is a major requirement for transvaginal meshes for pelvic organ prolapse (POP) repair. Polyvinylidene fluoride (PVDF) presented good characteristics in prior animal experiments and clinical use in humans. Methods: Between 01/2012 and 04/2016 37 women underwent transvaginal repair of symptomatic prolapse of the anterior vaginal wall (cystocele) with PVDF-mesh in a single institution. A chart review for recurrence, continence, peri-and early postoperative complications was performed. Referring practitioners were interviewed by telephone and mail. Additionally patient reported outcome and satisfaction were measured by Patient Global Improvement Inventory (PGI-I) scale. Results: 34 women were eligible for a mean follow up of 19 months. The functional outcome improved significantly. One symptomatic vault prolapse (2.9%) and two reoperations for incontinence (5.9%) occurred. Two mesh exposures (5.9%) occurred and were treated conservatively. No other severe complications were registered. 87.5% of treated women felt very much better or much better and would undergo the surgery again. A cohort study including development steps in accordance with the IDEAL system is presented. Conclusions: For the first time we report on effectivity and safety of transvaginal application of PVDF mesh in real-life practice. A prospective long-term evaluation in a registry is justified. (C)2017 IJS Publishing Group Ltd. Published by Elsevier Ltd. All rights reserved.

【 授权许可】

Free