Alpha blockers should no longer be used for ureteric stones

INTERNATIONAL JOURNAL OF SURGERY

卷:36

Review

Wiseman, Oliver J.¹  McClinton, Sam² 

[1] Cambridge Univ Hosp NHS Trust, Cambridge, England

[2] Univ Aberdeen, Acad Urol Unit, Aberdeen, Scotland

关键词: Urolithiasis;    Alpha-blocker;    Tamsulosin;    Ureteric stone;    Colic;   

DOI  :  10.1016/j.ijsu.2016.11.006

来源: Elsevier

【 摘 要 】

Alpha-blockers have been used as medical expulsive therapy for ureteric stones for a number of years. Conventional wisdom supporting their use has recently been challenged by the publication of a large, multi-centre, randomised double-blinded, placebo-controlled study, SUSPEND, which showed that they were ineffective. This paper looks at the evidence behind the use of alpha-blockers, and discusses why we should believe the evidence we have from SUSPEND, rather than other published studies, and therefore stop using them as medical expulsive therapy. (c) 2016 IJS Publishing Group Ltd. Published by Elsevier Ltd. All rights reserved.

【 授权许可】

Free