期刊论文详细信息
JOURNAL OF HEPATOLOGY 卷:71
Current knowledge in pathophysiology and management of Budd-Chiari syndrome and non-cirrhotic non-tumoral splanchnic vein thrombosis
Review
Hernandez-Gea, Virginia1  De Gottardi, Andrea2,3  Leebeek, Frank W. G.4  Rautou, Pierre-Emmanuel5,6  Salem, Riad7  Carlos Garcia-Pagan, Juan1 
[1] Univ Barcelona, Barcelona Hepat Hemodynam C Lab, Liver Unit, Hosp Clin Barcelona,IDIBAPS,CIBERehd,European Ref, Barcelona, Spain
[2] Univ Bern, Hepatol, Univ Clin Visceral Med & Surg, Inselspital, Bern, Switzerland
[3] Univ Bern, Dept Biomed Res, Bern, Switzerland
[4] Erasmus Univ, Med Ctr, Dept Haematol, Rotterdam, Netherlands
[5] DHU Unity, AP HP, Serv Hepatol,Hop Beaujon, Ctr Reference Malad Vasc Foie,Rile Malad Appareil, Clichy, France
[6] PARCC, Paris Cardiovasc Res Ctr, UMR 970, INSERM, Paris, France
[7] Northwestern Univ, Dept Radiol, Sect Intervent Radiol, Chicago, IL 60611 USA
关键词: Portal vein thrombosis;    Portal hypertension;    Thrombophilia;    Coagulopathy;    Transplant;    TIPS;    Angioplasty;   
DOI  :  10.1016/j.jhep.2019.02.015
来源: Elsevier
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【 摘 要 】

Budd-Chiari syndrome and non-cirrhotic non-tumoral portal vein thrombosis are 2 rare disorders, with several similarities that are categorized under the term splanchnic vein thrombosis. Both disorders are frequently associated with an underlying prothrombotic disorder. They can cause severe portal hypertension and usually affect young patients, negatively influencing life expectancy when the diagnosis and treatment are not performed at an early stage. Yet, they have specific features that require individual consideration. The current review will focus on the available knowledge on pathophysiology, diagnosis and management of both entities. (C) 2019 European Association for the Study of the Liver. Published by Elsevier B.V. All rights reserved.

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