The influence of Arsenic on the toxicity of carbon nanoparticles in bivalves

JOURNAL OF HAZARDOUS MATERIALS

卷:358

Article

Freitas, Rosa^1,2  Coppola, Francesca^1,2  De Marchi, Lucia^1,2  Codella, Valeria^1,2  Pretti, Carlo³  Chiellini, Federica⁴  Morelli, Andrea⁴  Polese, Gianluca⁵  Soares, Amadeu M. V. M.^1,2  Figueira, Etelvina^1,2 

[1] Univ Aveiro, Dept Biol, P-3810193 Aveiro, Portugal

[2] Univ Aveiro, Ctr Environm & Marine Studies CESAM, P-3810193 Aveiro, Portugal

[3] Univ Pisa, Dept Vet Sci, I-56122 Pisa, Italy

[4] Univ Pisa, Udr INSTM Pisa, Dept Chem & Ind Chem, I-56120 Pisa, Italy

[5] Univ Napoli Federico II, Dept Biol, I-80126 Naples, Italy

关键词: Mixture of contaminants;    Metabolism;    Oxidative stress;    Neurotoxicity;    Ruditapes philippinctrum;    Functionalized multi-walled carbon nanotubes;   

DOI  :  10.1016/j.jhazmat.2018.05.056

来源: Elsevier

【 摘 要 】

Although an increasing number of studies have been published on the effects of emergent pollutants such as carbon nanoparticles, there is still scarce information on the impact of these contaminants on marine organisms when acting in combination with classical pollutants such as meta(loid)s. The present study evaluated the impacts of Arsenic and Multi-Walled Carbon Nanotubes (MWCNTs) in the clam Ruditapes phikapinarum, assessing the effects induced when both contaminants were acting individually (As, NP) and as a mixture (As + NP). Metabolic capacity (electron transport system activity), oxidative stress (antioxidant and biotransformation enzymes activity and cellular damage) and neurotoxicity (Acetylcholinesterase activity) biomarkers were evaluated in clams after a 28 days exposure period. The results obtained showed that the accumulation of As was not affected by the presence of the NPs. Our results demonstrated that higher injuries were noticed in clams exposed to NPs, with higher metabolic depression and oxidative stress, regardless of the presence of As. Furthermore, higher neurotoxicity was observed in clams exposed to the combination of both contaminants in comparison to the effects of As and NPs individually.

【 授权许可】

Free