Soil-sebum partition coefficients for high molecular weight polycyclic aromatic hydrocarbons (HMW-PAH)

JOURNAL OF HAZARDOUS MATERIALS

卷:398

Article

Beriro, Darren J.¹  Cave, Mark¹  Kim, Alex¹  Craggs, Jonathan²  Wragg, Joanna¹  Thomas, Russell³  Taylor, Christopher⁴  Nathanail, C. Paul^1,5  Vane, Christopher¹ 

[1] British Geol Survey, Nicker Hill, Keyworth NG12 5GG, Notts, England

[2] Univ Nottingham, Sch Geog, Univ Pk, Nottingham, England

[3] WSP, WSP House,70 Chancery Lane, London WC2A 1AF, England

[4] Natl Grid Property Holdings Ltd, Natl Grid House,Warwick Technol Pk,Gallows Hill, Warwick CV34 6DA, England

[5] Univ Nottingham, Land Qual Management, Sir Colin Campbell Bldg,Innovat Pk, Nottingham NG7 2TU, England

关键词: Dermal;    Bioavailability;    Percutaneous;    Skin;    Bioaccessibility;   

DOI  :  10.1016/j.jhazmat.2020.122633

来源: Elsevier

【 摘 要 】

In vitro high molecular weight polycyclic aromatic hydrocarbons (HMW-PAH) soil-sebum partition coefficients (K-SS) were measured for twelve soils collected from former UK gasworks. Concentrations of Sigma 16 USEPA PAH in the soils ranged from 51 to 1440 mg/kg. Time series extractions (0.5, 1, 2, 4, 8 and 24 h) at skin temperature (32 degrees C) of HMW-PAH from sebum to soil for two samples were conducted to determine the maximum release time-step. The maximum HMW-PAH release time-step was determined as 4 h, which was subsequently used as the extraction time for the remaining samples. The 4 h extraction for all samples showed HMW-PAH K-SS ranging from 0.06 to 1.4 (median = 0.59; mean= 0.59; standard deviation = 0.27; median absolute deviation = 0.29). Evaluation of KSS data for the 4 h extractions showed that soil type and selected HMW-PAH properties (literature based molecular weight and octanol-carbon partition coefficients) affect the amount of HMW-PAH released from soil into sebum.

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