Association of disclosure of HIV status with medication adherence

PATIENT EDUCATION AND COUNSELING

卷:99

Article

Rotzinger, Aurelie^1,2  Locatelli, Isabella³  Reymermier, Matthias²  Amico, Sebastian²  Bugnon, Olivier^1,2  Cavassini, Matthias^4,5  Schneider, Marie Paule^1,2 

[1] Univ Lausanne, Univ Geneva, Sch Pharmaceut Sci, Community Pharm, Geneva, Switzerland

[2] Univ Lausanne, Dept Ambulatory Care & Community Med, Community Pharm, Lausanne, Switzerland

[3] Univ Lausanne, Dept Ambulatory Care & Community Med, Lausanne, Switzerland

[4] Univ Lausanne Hosp, Infect Dis Serv, Lausanne, Switzerland

[5] Univ Lausanne, Lausanne, Switzerland

关键词: Medication adherence;    Disclosure;    HIV;    Social support;    Refusal to participate;   

DOI  :  10.1016/j.pec.2016.03.012

来源: Elsevier

【 摘 要 】

Objective: Disclosure may affect adherence to antiretroviral treatment. In a medication adherence program, this cross-sectional study describes disclosure, perceived reaction after disclosure, living situations, and the relationship of disclosure with antiretroviral adherence. Methods: A combination of a questionnaire to measure disclosure and longitudinal electronic monitoring of medication adherence was used. Results: A total of 103 out of 159 eligible patients gave informed consent. The characteristics differed between participants and nonparticipants (race, education, sexual orientation, medication adherence). Thirteen participants did not disclose their HIV status. Seventy-three (81%) participants judged the reaction after disclosure positive. Among the 62 participants cohabiting, 52% disclosed to all co-residents. Adherence was high (median 100%). HIV disclosure was negatively associated with adherence, when disclosing to the mother (OR = 2.46, p-value = 0.086) and to siblings (OR = 2.89, p-value = 0.029). Living alone was associated to a lower adherence than cohabitation (Rate Ratio = 1.42, p-value = 0.007). Conclusion: HIV disclosure and adherence are sensitive issues, which may explain the reason for refusal. Nonparticipants may be those with the most difficulties disclosing. Practice implications: An unbiased collection of sensitive information, as HIV disclosure, is a difficult task. A cohort design, with research data collected systematically by a trusted healthcare provider, may better describe the association between adherence and disclosure. (C) 2016 Elsevier Ireland Ltd. All rights reserved.

【 授权许可】

Free