Connecting brain and behavior in clinical neuroscience: A network approach

NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

卷:130

Article

Blanken, Tessa F.¹  Bathelt, Joe²  Deserno, Marie K.³  Voge, Lily⁴  Borsboom, Denny¹  Douw, Linda^4,5 

[1] Univ Amsterdam, Dept Psychol Methods, NL-1018 WT Amsterdam, Netherlands

[2] Royal Holloway Univ London, Dept Psychol, Egham TW20 0EX, Surrey, England

[3] Max Planck Inst Human Dev, D-14195 Berlin, Germany

[4] Vrije Univ Amsterdam, Amsterdam Univ Med Ctr, Dept Anat & Neurosci, Amsterdam Neurosci, NL-1081 HZ Amsterdam, Netherlands

[5] Massachusets Gen Hosp, Athinoula A Martinos Ctr Biomed Imaging, Dept Radiol, Boston, MA 02129 USA

关键词: Brain;    Behavior;    Network science;    Psychopathology;    Clinical neuroscience;    Graph theory;   

DOI  :  10.1016/j.neubiorev.2021.07.027

来源: Elsevier

【 摘 要 】

In recent years, there has been an increase in applications of network science in many different fields. In clinical neuroscience and psychopathology, the developments and applications of network science have occurred mostly simultaneously, but without much collaboration between the two fields. The promise of integrating these network applications lies in a united framework to tackle one of the fundamental questions of our time: how to understand the link between brain and behavior. In the current overview, we bridge this gap by introducing conventions in both fields, highlighting similarities, and creating a common language that enables the exploitation of synergies. We provide research examples in autism research, as it accurately represents research lines in both network neuroscience and psychological networks. We integrate brain and behavior not only semantically, but also practically, by showcasing three methodological avenues that allow to combine networks of brain and behavioral data. As such, the current paper offers a stepping stone to further develop multi-modal networks and to integrate brain and behavior.

【 授权许可】

Free