Motivation and cognitive control in depression

NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

卷:102

Review

Grahek, Ivan¹  Shenhav, Amitai^2,3  Musslick, Sebastian⁴  Krebs, Ruth M.⁵  Koster, Ernst H. W.¹ 

[1] Univ Ghent, Dept Expt Clin & Hlth Psychol, Henri Dunantlaan 2, B-9000 Ghent, Belgium

[2] Brown Univ, Dept Cognit Linguist & Psychol Sci, Providence, RI 02912 USA

[3] Brown Univ, Brown Inst Brain Sci, Providence, RI 02912 USA

[4] Princeton Univ, Princeton Neurosci Inst, Princeton, NJ 07001 USA

[5] Univ Ghent, Dept Expt Psychol, Henri Dunantlaan 2, B-9000 Ghent, Belgium

关键词: Depression;    Cognitive control;    Anhedonia;    Motivation;    Reward anticipation;    Effort;    Controllability of environment;   

DOI  :  10.1016/j.neubiorev.2019.04.011

来源: Elsevier

【 摘 要 】

Depression is linked to deficits in cognitive control and a host of other cognitive impairments arise as a consequence of these deficits. Despite of their important role in depression, there are no mechanistic models of cognitive control deficits in depression. In this paper we propose how these deficits can emerge from the interaction between motivational and cognitive processes. We review depression-related impairments in key components of motivation along with new cognitive neuroscience models that focus on the role of motivation in the decision-making about cognitive control allocation. Based on this review we propose a unifying framework which connects motivational and cognitive control deficits in depression. This framework is rooted in computational models of cognitive control and offers a mechanistic understanding of cognitive control deficits in depression.

【 授权许可】

Free