Hair cortisol: A new tool for evaluating stress in programs of stress management

LIFE SCIENCES

卷:141

Article

Iglesias, Silvia¹  Jacobsen, Dario²  Gonzalez, Diego²  Azzara, Sergio³  Repetto, Esteban M.²  Jamardo, Juan²  Garin Gomez, Sabrina²  Mesch, Viviana²  Berg, Gabriela²  Fabre, Bibiana² 

[1] Univ Buenos Aires, Fac Pharm & Biochem, RA-1053 Buenos Aires, DF, Argentina

[2] Univ Buenos Aires, Fac Pharm & Biochem, INFIBIOC, Dept Clin Biochem, RA-1053 Buenos Aires, DF, Argentina

[3] Univ Buenos Aires, Fac Psychol, RA-1053 Buenos Aires, DF, Argentina

关键词: Hair cortisol;    Salivary cortisol;    Stress management;   

DOI  :  10.1016/j.lfs.2015.10.006

来源: Elsevier

【 摘 要 】

Aims: Longitudinal and experimental studies have shown that chronic stress contributes to the onset and progression of different diseases. Although it is not possible to eliminate stress completely, people can learn to manage it by participating in different kinds of stress management interventions. This study examined the effectiveness of stress management interventions on neuroendocrine responses in stressed students and health professionals, by measuring hair cortisol in comparison to salivary cortisol. Main methods: Salivary and hair cortisol measurements were performed in 37 subjects (31 women, 6 men; mean age 34.0 +/- 10.6) who attended to a Coping Stress and Quality of Care Program at the University of Buenos Aires. Cortisol was measured at the beginning and at the end of the program. The State-Trait Anxiety Inventory STAI was used to evaluate state and trait anxiety. Key findings: In subjects who completed the program, no differences were observed in salivary cortisol levels between the first and the last session. However, in these subjects, hair cortisol obtained in the last session was significantly lower than hair cortisol in the first session. Significance: Hair cortisol appears to be a better biomarker than salivary cortisol for evaluation of the effectiveness of a stress reduction program and it seems to be a better indicator of stress system dysregulation as well. (C) 2015 Elsevier Inc. All rights reserved.

【 授权许可】

Free