Nanoscale assembly of amine-functionalized colloidal iron oxide

JOURNAL OF MAGNETISM AND MAGNETIC MATERIALS

卷:321

Article; Proceedings Paper

Barick, K. C.²  Aslam, M.^3,6  Prasad, Pottumarthi V.⁴  Dravid, Vinayak P.^1,5  Bahadur, Dhirendra^2,6 

[1] Northwestern Univ, Dept Mat Sci & Engn, Evanston, IL 60208 USA

[2] Indian Inst Technol, Dept Met Engn & Mat Sci, Bombay 400076, Maharashtra, India

[3] Indian Inst Technol, Dept Phys, Bombay 400076, Maharashtra, India

[4] Evanston NW Healthcare, Dept Radiol, Evanston, IL 60201 USA

[5] Northwestern Univ, Int Inst Nanotechnol, Evanston, IL 60208 USA

[6] Indian Inst Technol, Ctr Res Nanotechnol & Sci, Bombay 400076, Maharashtra, India

关键词: Nanoparticle;    Nanoassembly;    MR contrast agent;    Surface functionalization;    Iron oxide;   

DOI  :  10.1016/j.jmmm.2009.02.080

来源: Elsevier

【 摘 要 】

We demonstrate a single-step facile approach for highly water-stable assembly of amine-functionalized Fe3O4 nanoparticles using thermal decomposition of Fe-chloride precursors in ethylene glycol medium in the presence of ethylenediamine. The average size of nanoassemblies is 40 perpendicular to 1 nm, wherein the individual nanoparticles are about 6nm. Amine-functionalized properties are evident from Fourier transform infrared spectrometer (FTIR), thermal and elemental analyses. The saturation magnetization and spin-echo r(2) of the nanoassemblies were measured to be 64.3emu/g and 314.6 mM(-1) s(-1), respectively. The higher value of relaxivity ratio(r(2)/r(1) = 143) indicates that nanoassemblies are a promising high-efficiency T2 contrast agent platform. & 2009 Elsevier B.V. All rights reserved.

【 授权许可】

Free