Advanced imaging techniques (CT and MR): Gender-based diagnostic work-up in ischemic heart disease?

INTERNATIONAL JOURNAL OF CARDIOLOGY

卷:286

Article

Guaricci, Andrea Igoren¹  Carrabba, Nazario²  Aquaro, Giovanni Donato³  Rabbat, Mark G.^4,5  Gaemperli, Oliver⁶  Ducci, Chiara Bucciarelli⁷  Pontone, Gianluca⁸ 

[1] Univ Hosp Policlin Bari, Dept Emergency & Organ Transplantat, Inst Cardiovasc Dis, Bari, Italy

[2] Careggi Hosp, Cardiovasc & Thorac Dept, Florence, Italy

[3] Fdn G Monasterio CNR Reg Toscana Pisa, UOC Risonanza Magnet Immagini, Pisa, Italy

[4] Loyola Univ, Chicago, IL 60611 USA

[5] Edward Hines Jr VA Hosp, Hines, IL USA

[6] Univ Hosp Zurich, Univ Heart Ctr, Zurich, Switzerland

[7] Bristol Heart Inst, Bristol NIHR Cardiovasc Biomed Res Unit, Bristol, Avon, England

[8] IRCCS, Ctr Cardiol Monzino, Via C Parea 4, I-20138 Milan, Italy

关键词: Cardiac computed tomography;    Cardiac magnetic resonance;    Diagnosis;    Gender;    Prognosis;   

DOI  :  10.1016/j.ijcard.2018.11.010

来源: Elsevier

【 摘 要 】

It is ascertained that the epidemiology and social impact of ischemic heart disease is substantially different between the two genders. Moreover, there is substantial evidence that gender is able to modulate the clinical manifestation of most cardiac diseases, and specifically of coronary artery disease. Particularly, women present less angiographically significant coronary artery disease, smaller vessel lumen, and less plaque rupture occurrence as compared to men. On the contrary, manifestations as vasospasm, impaired vasodilatation at epicardial level, and microvascular dysfunction are more common in female. In clinical practice, it is important to know the gender-based aspects of clinical disease expression and how to diversify the diagnostic work-up. Cardiac Computed Tomography and Cardiac Magnetic Resonance are relatively new diagnostic imaging tools employed for studying both the cardiac structures and the pathophysiology of the cardiovascular system. In this paper, we aim to overview the non-invasive diagnostic role in a gender's dimension, mainly focusing on Cardiac Computed Tomography and Cardiac Magnetic Resonance in ischemic heart disease, and to understand whether the existing evidences support a different diagnostic work-up approach. (C) 2018 Elsevier B.V. All rights reserved.

【 授权许可】

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