Cardiopulmonary Impact of Particulate Air Pollution in High-Risk Populations JACC State-of-the-Art Review

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

卷:76

Review

Newman, Jonathan D.^1,2  Bhatt, Deepak L.^3,4  Rajagopalan, Sanjay⁵  Balmes, John R.⁶  Brauer, Michael⁷  Breysse, Patrick N.⁸  Carnethon, Mercedes R.¹⁰  Cascio, Wayne E.¹¹  Collman, Gwen W.¹²  Fine, Lawrence J.⁹  Hansel, Nadia N.¹³  Hernandez, Adrian¹⁴  Hochman, Judith S.¹⁵  Jerrett, Michael¹⁶  Joubert, Bonnie R.¹⁷  Kaufman, Joel D.^18,19,20  Malik, Ali O.²¹  Mensah, George A.²²  Newby, David E.²³  Peel, Jennifer L.²⁴  Siegel, Jeffrey^25,26  Siscovick, David²⁷  Thompson, Betsy L.²⁸  Zhang, Junfeng^29,30  Brook, Robert D.³¹ 

[1] NYU, Grossman Sch Med, Div Cardiol, New York, NY USA

[2] NYU, Grossman Sch Med, Ctr Prevent Cardiovasc Dis, New York, NY USA

[3] Brigham & Womens Hosp, Heart & Vasc Ctr, 75 Francis St, Boston, MA 02115 USA

[4] Harvard Med Sch, Boston, MA 02115 USA

[5] Case Western Reserve Univ, Univ Hosp, Harrington Heart & Vasc Inst, Cleveland, OH 44106 USA

[6] Univ Calif San Francisco, Dept Med, Div Pulm Crit Care Allergy & Sleep Med, San Francisco, CA 94143 USA

[7] Univ British Columbia, Sch Populat & Publ Hlth, Vancouver, BC, Canada

[8] Ctr Dis Control & Prevent, Natl Ctr Environm Hlth, Agcy Tox Subst & Dis Registry, Atlanta, GA USA

[9] NHLBI, Div Cardiovasc Sci, Washington, DC USA

[10] Northwestern Univ, Feinberg Sch Med, Dept Prevent Med, Chicago, IL 60611 USA

[11] US Environm Protect Agcy, Ctr Publ Hlth & Environm Assessment, Durham, NC USA

[12] NIEHS, Durham, NC USA

[13] Johns Hopkins Univ, Dept Med, Div Pulm & Crit Care Med, Baltimore, MD USA

[14] Duke Univ, Sch Med, Clin Res, Durham, NC USA

[15] NYU, Grossman Sch Med, New York, NY USA

[16] Univ Calif Los Angeles, Fielding Sch Publ Hlth, Los Angeles, CA USA

[17] NIEHS, Populat Hlth Branch, Div Extramural Res & Training, Durham, NC USA

[18] Univ Washington, Dept Environm & Occupat Hlth Sci, Seattle, WA 98195 USA

[19] Univ Washington, Dept Med, Seattle, WA 98195 USA

[20] Univ Washington, Dept Epidemiol, Seattle, WA 98195 USA

[21] St Lukes Mid Amer Heart Inst, Kansas City, MO USA

[22] NHLBI, Ctr Translat Res & Implementat Sci, Washington, DC USA

[23] Univ Edinburgh, British Heart Fdn Ctr Cardiovasc Sci, Edinburgh, Midlothian, Scotland

[24] Colorado State Univ, Dept Environm & Radiol Hlth Sci, Ft Collins, CO 80523 USA

[25] Univ Toronto, Dept Civil & Mineral Engn, Toronto, ON, Canada

[26] Univ Toronto, Dalla Lana Sch Publ Hlth, Toronto, ON, Canada

[27] New York Acad Med, Div Res Evaluat & Policy, New York, NY USA

[28] Ctr Dis Control & Prevent, Div Heart Dis & Stroke Prevent, Atlanta, GA USA

[29] Duke Univ, Nicholas Sch Environm, Durham, NC USA

[30] Duke Univ, Duke Global Hlth Inst, Durham, NC USA

[31] Wayne State Univ, Div Cardiovasc Dis, Detroit, MI USA

关键词: cardiopulmonary disease;    cardiovascular disease;    fine particulate air pollution;    portable air cleaner;    randomized clinical trials;   

DOI  :  10.1016/j.jacc.2020.10.020

来源: Elsevier

【 摘 要 】

Fine particulate air pollution <2.5 mu m in diameter (PM2.5) is a major environmental threat to global public health. Multiple national and international medical and governmental organizations have recognized PM2.5 as a risk factor for cardiopulmonary diseases. A growing body of evidence indicates that several personal-level approaches that reduce exposures to PM2.5 can lead to improvements in health endpoints. Novel and forward-thinking strategies including randomized clinical trials are important to validate key aspects (e.g., feasibility, efficacy, health benefits, risks, burden, costs) of the various protective interventions, in particular among real-world susceptible and vulnerable populations. This paper summarizes the discussions and conclusions from an expert workshop, Reducing the Cardiopulmonary Impact of Particulate Matter Air Pollution in High Risk Populations, held on May 29 to 30, 2019, and convened by the National Institutes of Health, the U.S. Environmental Protection Agency, and the U.S. Centers for Disease Control and Prevention. (C) 2020 the American College of Cardiology Foundation. Published by Elsevier. All rights reserved.

【 授权许可】

Free