Highly efficient asymmetric-axle-supported N-O amides in enantioselective hydrosilylation of ketimines with trichlorosilane

TETRAHEDRON

卷:69

Article

Pan, Wei^1,4  Deng, Yu^1,4  He, Jiang-Bo^1,4  Bai, Bing¹  Zhu, Hua-Jie^1,2,3 

[1] Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650204, Peoples R China

[2] Hebei Univ, Key Lab Med Chem & Mol Diag, Minist Educ, Baoding 071002, Peoples R China

[3] Hebei Univ, Sch Life Sci, Baoding 071002, Peoples R China

[4] Grad Univ CAS, Beijing, Peoples R China

关键词: Asymmetric-axle-supported;    Hydrosilylation;    Ketimines;    Trichlorosilane;   

DOI  :  10.1016/j.tet.2013.06.081

来源: Elsevier

【 摘 要 】

A novel asymmetric-axle-supported chiral N-O amide was synthesized and used in catalytic enantioselective hydrosilylation of N-aryl ketimines with HSiCl3 at room temperature instead of the typical -20 degrees C. High conversion yield and high enantioselectivity up to 96% were observed. (C) 2013 The Authors. Published by Elsevier Ltd. All rights reserved.

【 授权许可】

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