Synthesis of trisaccharide-coated magnetic nanoparticles for antibody removal

TETRAHEDRON

卷:73

Article

Yan, Shuaihu^1,2  Zhao, Cuixia²  Ren, Qidong^1,2  Xie, Xinni¹  Yang, Feng³  Du, Yuguo^1,2 

[1] Chinese Acad Sci, Res Ctr Ecoenvironm Sci, State Key Lab Environm Chem & Ecotoxicol, Beijing 100085, Peoples R China

[2] Chinese Acad Sci, Sch Chem & Chem Engn, Grad Univ, Beijing 100049, Peoples R China

[3] Wuhan Borenpharm Co Ltd, Wuhan 430073, Peoples R China

关键词: Blood group A;    Antigen;    Carbohydrate;    MNPs;    Glyco-NPs;   

DOI  :  10.1016/j.tet.2017.04.003

来源: Elsevier

【 摘 要 】

An efficient strategy for the synthesis of blood group A trisaccharide antigen has been developed. Magnetic nanoparticles having Fe3O4-Silica core-shell structure were prepared and functionalized with the prepared blood group A trisaccharide antigen derivative, and its excellent removal ability toward anti-A antibody was explored. (C) 2017 Elsevier Ltd. All rights reserved.

【 授权许可】

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