RhCl3/amine-catalyzed [2+2+2] cyclization of alkynes

TETRAHEDRON

卷:64

Article

Yoshida, Kenta¹  Morimoto, Ichiro¹  Mitsudo, Koichi¹  Tanaka, Hideo¹ 

[1] Okayama Univ, Grad Sch Nat Sci & Technol, Div Chem & Biochem, Okayama 7008530, Japan

关键词: Rh/amine catalyst;    cyclotrimerization;    hexa-substituted benzene;   

DOI  :  10.1016/j.tet.2008.03.079

来源: Elsevier

【 摘 要 】

The RhCl3-3H(2)O/i-Pr2NEt-catalyzed [2+2+2] cyclotrimerization of alkynes has been achieved. The reaction can be widely used for various alkynes and provides tri- OF hexa-substituted benzenes regioselectively in high yields. The [2+2+2] cycloaddition of diynes and alkynes is also developed, and it affords benzene derivatives in moderate to high yields. (C) 2008 Elsevier Ltd. All rights reserved.

【 授权许可】

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