An easy access to fused chromanones via rhodium catalyzed oxidative coupling of salicylaldehydes with heterobicyclic olefins

TETRAHEDRON

卷:72

Article

Vijayan, Ajesh^1,2  Baiju, T. V.^1,2  Jiiy, E.¹  Prakash, Praveen¹  Shimi, M.^1,2  Joseph, Nayana¹  Pihko, Petri M.³  Varughese, Sunil⁴  Radhakrishnan, K. V.^1,2 

[1] CSIR, Natl Inst Interdisciplinary Sci & Technol, Chem Sci & Technol Div, Organ Chem Sect, Trivandrum 695019, Kerala, India

[2] Acad Sci & Innovat Res AcSIR, New Delhi 110001, India

[3] Univ Jyvaskyla, Dept Chem, SF-40351 Jyvaskyla, Finland

[4] CSIR, Natl Inst Interdisciplinary Sci & Technol, Chem Sci & Technol Div, Inorgan Chem Sect, Trivandrum 695019, Kerala, India

关键词: Chromanone;    Rhodium catalyzed;    Diazabicyclic olefins;    Urea derived bicyclic olefins;    Salicylaldehyde;   

DOI  :  10.1016/j.tet.2016.05.031

来源: Elsevier

【 摘 要 】

Herein we describe a detailed study on the rhodium catalyzed oxidative coupling of salicylaldehydes with heterobicyclic olefins such as diazabicyclic olefins and urea-derived bicyclic olefins. The developed method provides an ideal route to fused chromanone systems in a single synthetic step. Moreover, the scope of this methodology was extended to different oxa/aza-bridged bicyclic urea derivatives. (C) 2016 Elsevier Ltd. All rights reserved.

【 授权许可】

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