Selective C-O bond formation: highly efficient radical dioxygenation of alkenes initiated by catalytic amount of tert-butyl hydroperoxide

TETRAHEDRON

卷:72

Article

Xia, Xiao-Feng¹  Zhu, Su-Li¹  Hu, Qing-Tao¹  Chen, Chao¹ 

[1] Jiangnan Univ, Sch Chem & Mat Engn, Key Lab Food Colloids & Biotechnol, Minist Educ, Wuxi 214122, Jiangsu, Peoples R China

关键词: Dioxygenation;    Hydroxamic acid;    Radical addition;    Selective oxidation;    1-Phenylethanol;   

DOI  :  10.1016/j.tet.2016.10.029

来源: Elsevier

【 摘 要 】

A highly selective radical dioxygenation of alkenes using hydroxamic acid and O-2 with 5-10 mol % of tert-butyl hydroperoxide as a catalyst was developed. On the basis of this newly developed strategy, a wide range of phenylethanol derivatives with a variety of functional groups can be effectively synthesized. (C) 2016 Elsevier Ltd. All rights reserved.

【 授权许可】

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