Synthesis and identification of metabolite biomarkers of 25C-NBOMe and 25I-NBOMe

TETRAHEDRON

卷:73

Article

Wu, Xiongyu¹  Eriksson, Caroline¹  Wohlfarth, Ariane^2,3  Wallgren, Jakob¹  Kronstrand, Robert^2,3  Josefsson, Martin^2,3  Dahlen, Johan¹  Konradsson, Peter¹ 

[1] Linkoping Univ, Dept Phys Chem & Biol, Linkoping, Sweden

[2] Natl Board Forens Med, Dept Forens Genet & Forens Toxicol, Linkoping, Sweden

[3] Linkoping Univ, Div Drug Res, Dept Med & Hlth Sci, Fac Hlth Sci, Linkoping, Sweden

关键词: Biomarker;    25C-NBOMe;    25I-NBOMe;    Metabolite;    Urinary detection;   

DOI  :  10.1016/j.tet.2017.09.024

来源: Elsevier

【 摘 要 】

Synthetic routes have been developed for synthesis of potential metabolites of 25C-NBOMe and 25I-NBOMe. Nine potential metabolites have been synthesized, among which compounds 8 and 20a could be used as metabolite biomarkers of 25C-NBOMe and 20b of 25I-NBOMe in urinary detection at forensic laboratories to prove intake. (C) 2017 Elsevier Ltd. All rights reserved.

【 授权许可】

Free