One-pot aqueous synthesis of gadolinium doped CdTe quantum dots with dual imaging modalities

TALANTA

卷:155

Article

Jiang, Chunli¹  Shen, Zhitao²  Luo, Chunhua¹  Lin, Hechun¹  Huang, Rong¹  Wang, Yiting²  Peng, Hui¹ 

[1] E China Normal Univ, Minist Educ, Key Lab Polar Mat & Devices, Shanghai 200241, Peoples R China

[2] E China Normal Univ, Coll Chem & Mol Engn, Shanghai 200241, Peoples R China

关键词: Aqueous synthesis;    Gd doped CdTe;    Quantum dots;    Fluorescence;    MR imaging;   

DOI  :  10.1016/j.talanta.2016.04.021

来源: Elsevier

【 摘 要 】

A facile one-pot strategy has been developed for the aqueous synthesis of Gd doped CdTe (Gd:CdTe) QDs as fluorescence and magnetic resonance imaging dual-modal agent. The prepared Gd:CdTe QDs showed narrow size distribution and the average size was less than 5 nm. The amount of Gd3+ dopant in Gd:CdTe QDs significantly affected the optical properties of obtained QDs. The highest PL QY for the prepared Gd: CdTe QDs was up to 42.5%. The QDs showed the weak toxicity and significant enhancement in MRI signal. The specific relaxivity value (r1) was determined to be 4.22 mM(-1)s(-1). These properties make the prepared Gd:CdTe QDs be an effective dual-modal imaging agent and have great potential applications in biomedical field. (C) 2016 Elsevier B.V. All rights reserved.

【 授权许可】

Free