Photonic crystal based biosensors: Emerging inverse opals for biomarker detection

TALANTA

卷:221

Review

Fathi, Farzaneh¹  Rashidi, Mohammad-Reza²  Pakchin, Parvin Samadi³  Ahmadi-Kandjani, Sohrab⁴  Nikniazi, Arash^4,5 

[1] Ardabil Univ Med Sci, Pharmaceut Sci Res Ctr, Ardebil, Iran

[2] Tabriz Univ Med Sci, Fac Pharm, Tabriz, Iran

[3] Tabriz Univ Med Sci, Res Ctr Pharmaceut Nanotechnol, Biomed Inst, Tabriz, Iran

[4] Univ Tabriz, Res Inst Appl Phys & Astron, Photon Grp, Tabriz, Iran

[5] Queens Univ, Dept Phys Engn Phys & Astron, Kingston, ON, Canada

关键词: Photonic crystal;    Inverse opal;    Biomarker detection;   

DOI  :  10.1016/j.talanta.2020.121615

来源: Elsevier

【 摘 要 】

Photonic crystal (PC)-based inverse opal (IO) arrays are one of the substrates for label-free sensing mechanism. IO-based materials with their advanced and ordered three-dimensional microporous structures have recently found attractive optical sensor and biological applications in the detection of biomolecules like proteins, DNA, viruses, etc. The unique optical and structural properties of IO materials can simplify the improvements in non-destructive optical study capabilities for point of care testing (POCT) used within a wide variety of biosensor research. In this review, which is an interdisciplinary investigation among nanotechnology, biology, chemistry and medical sciences, the recent fabrication methodologies and the main challenges regarding the application of (inverse opals) IOs in terms of their bio-sensing capability are summarized.

【 授权许可】

Free