Permeation control in hydrogel-layered patterned PET membranes with defined switchable pore geometry - Experiments and numerical simulation

SENSORS AND ACTUATORS B-CHEMICAL

卷:232

Article

Ehrenhofer, Adrian¹  Bingel, Gert²  Paschew, Georgi²  Tietze, Marcus²  Schroeder, Raoul³  Richter, Andreas²  Wallmersperger, Thomas¹ 

[1] Tech Univ Dresden, Inst Festkorpermech, D-01062 Dresden, Germany

[2] Tech Univ Dresden, Inst Halbleiter Mikrosyst Tech, D-01062 Dresden, Germany

[3] Burkert Fluid Control Syst, Christian Burkert Str 13-17, D-74653 Ingelfingen, Germany

关键词: Polymeric membranes;    Finite element simulation;    Hydrogel swelling;    Microfluidics;    Micromechanical pore valve;    Particle separation;   

DOI  :  10.1016/j.snb.2016.03.152

来源: Elsevier

【 摘 要 】

Permeation through polymeric membranes can be controlled by surface coating of a polyethylene terephthalate (PET) membrane with poly(N-isopropylacrylamide) (PNIPAAm) and inserting pores of defined geometry. When the temperature of the system rises above the volume phase transition temperature, the pores open, which allows permeation of formerly blocked particles. The exact control of the temperature allows defined change of the pore size and therefore enables separation abilities. Free swelling experiments are conducted to obtain the swelling behaviour of PNIPAAm. Then, a temperature expansion model is derived in order to simulate this behaviour with the finite element tool ABAQUS. The gained results are in excellent agreement with the observed shape change. Membranes with permeation control of particles can be used for biomedical application in microfluidics to analyse the size distribution of cells or in chemical information processing as a transistor-like component for an information-bearing chemical species. The possibility to simulate the behaviour of such permeation systems allows computer aided design and prediction of permeation abilities in these areas. (C) 2016 The Authors. Published by Elsevier B.V. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

【 授权许可】

Free