Integrating optical waveguides in electrowetting-on-dielectric digital microfluidic chips

SENSORS AND ACTUATORS B-CHEMICAL

卷:181

Article

Ceyssens, Frederik¹  Witters, Daan²  Van Grimbergen, Thom¹  Knez, Karel²  Lammertyn, Jeroen²  Puers, Robert¹ 

[1] KULeuven, Dept ESAT MICAS, B-3000 Louvain, Belgium

[2] KULeuven, Dept MeBios, B-3001 Louvain, Belgium

关键词: EWOD;    Digital lab-on-chip;    Lab-on-chip;    Waveguides;    Optical waveguides;    Electrowetting;    Gold nanoparticles;   

DOI  :  10.1016/j.snb.2013.01.078

来源: Elsevier

【 摘 要 】

Readout through a microscope-based setup is one of the most prevalent optical detection methods used in current digital (i.e. droplet-based) electrowetting-on-dielectric lab-on-chip devices. The integration of waveguides on such devices allows further size and complexity reduction for absorption, fluorescence and surface plasmon resonance based detection mechanisms. In this paper, we show a straightforward method to integrate multimode polymer optical waveguides on an EWOD device. A proof-of-concept system is presented that allows droplets to be transported by EWOD actuation to a gap between two opposing waveguides down to 300 mu m in size, and engulf the integrated waveguides for transmission measurements. The system is validated using a gold nanoparticle based model assay. (C) 2013 Elsevier B.V. All rights reserved.

【 授权许可】

Free