Tuning microfluidic flow by pulsed light oscillating spiropyran-based polymer hydrogel valves

SENSORS AND ACTUATORS B-CHEMICAL

卷:245

Article

Coleman, Simon¹  ter Schiphorst, Jeroen²  Ben Azouz, Aymen¹  Bakker, Sterre²  Schenning, Albertus P. H. J.^2,3  Diamond, Dermot¹ 

[1] Dublin City Univ, Natl Ctr Sensor Res, Insight Ctr Data Analyt, Dublin, Ireland

[2] Dept Chem Engn & Chem, Funct Organ Mat & Devices, Eindhoven, Netherlands

[3] Eindhoven Univ Technol, Inst Complex Mol Syst, POB 513, NL-5600 MB Eindhoven, Netherlands

关键词: Photo-responsive;    Spiropyran;    Polymer;    Microfluidics;    Microvalves;    Flow control;   

DOI  :  10.1016/j.snb.2017.01.112

来源: Elsevier

【 摘 要 】

A method for microfluidic flow control based upon polymer hydrogel valves with rapid and reversible actuation properties is described. The platform allows for contactless optical flow control based upon pulsing light, resulting in a forced oscillating and control over the valve through photo-isomerisation of a spiropyran derivative, co-polymerised within an N-isopropylacrylamide (NIPAm) hydrogel. Application of pulsed light (450 nm) to the valves allows the valves to be held at an intermediate position for extended periods of time. Varying the extent of pulsing of the light source enables the flow rate to be regulated within a microfluidic flow rate range of 0-27 mu L/min. Due to the pulsed light, a small period change in the flow rate is observed that corresponds to the pulse sequence as a corresponding oscillation in the hydrogel valves. (C) 2017 Elsevier B.V. All rights reserved.

【 授权许可】

Free