Preparation of novel optical fibre-based Cocaine sensors using a molecular imprinted polymer approach

SENSORS AND ACTUATORS B-CHEMICAL

卷:193

Article

Wren, Stephen P.¹  Nguyen, T. Hien¹  Gascoine, Paul²  Lacey, Richard³  Sun, Tong¹  Grattan, Kenneth T. V.^1,4 

[1] City Univ London, Sch Engn & Math Sci, London EC1V 0HB, England

[2] Smiths Detect, Watford WD23 2BW, Herts, England

[3] Ctr Appl Sci & Technol, Home Off, St Albans AL4 9HQ, Herts, England

[4] City Univ London, City Grad Sch, London EC1V 0HB, England

关键词: Optical fibre sensor;    Chemical sensor;    Cocaine sensor;    Fluorescence;    Molecular imprinted polymer;    Interferants;   

DOI  :  10.1016/j.snb.2013.11.071

来源: Elsevier

【 摘 要 】

Novel chemical sensors using fibre optic-based techniques for the detection of Cocaine have been developed, utilising molecularly imprinted polymers (MIPs) containing fluorescein moieties as the signalling groups. The fluorescent MIPs were formed and covalently attached to the distal end of specially chosen optical fibres to create fibre optic probe-based sensors. These sensors exhibited are producible and quantifiable change in the intensity of the fluorescence signal received from the sensor in response to Cocaine in aqueous acetonitrile mixtures. High selectivity for Cocaine over Codeine and a range of known Cocaine interferants has been demonstrated for one of the sensors developed in this work. (C) 2013 Published by Elsevier B.V.

【 授权许可】

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