Optical biosensors based on ZnO nanostructures: advantages and perspectives. A review

SENSORS AND ACTUATORS B-CHEMICAL

卷:229

Review

Tereshchenko, Alla¹  Bechelany, Mikhael²  Viter, Roman³  Khranovskyy, Volodymyr⁴  Smyntyna, Valentyn¹  Starodub, Nikolay⁵  Yakimova, Rositza⁴ 

[1] Odessa Natl II Mechnikov Univ, Expt Phys Dept, Fac Phys, 42 Pastera, UA-65026 Odessa, Ukraine

[2] Univ Montpellier, UMR ENSCM UM CNRS 5635, Inst Europeen Membranes, Pl Eugene Bataillon, F-34095 Montpellier 5, France

[3] Univ Latvia, Inst Atom Phys & Spect, Rainis Blvd, LV-1586 Riga, Latvia

[4] Linkoping Univ, IFM, Inst Phys Math & Biol, S-58183 Linkoping, Sweden

[5] Natl Univ Life & Environm Sci, 15 Geroyiv Oborony, UA-03041 Kiev, Ukraine

关键词: Optical biosensors;    ZnO;    Nanostructures;    Immobilization;    Photoluminescence based biosensors;    Interaction mechanism;   

DOI  :  10.1016/j.snb.2016.01.099

来源: Elsevier

【 摘 要 】

This review article highlights the application of beneficial physico-chemical properties of ZnO nanostructures for the detection of wide range of biological compounds. As the medical diagnostics require accurate, fast and inexpensive biosensors, the advantages inherent optical methods of detection are considered. The crucial points of the immobilization process, responsible for biosensor performance (biomolecule adsorption, surface properties, surface defects role, surface functionalization etc.) along with the interaction mechanism between biomolecules and ZnO are disclosed. The latest achievements in surface plasmon resonance (SPR), surface enhanced Raman spectroscopy (SERS) and photoluminescence based biosensors along with novel trends in the development of ZnO biosensor platform are presented. (c) 2016 Elsevier B.V. All rights reserved.

【 授权许可】

Free