Effectiveness of hand hygiene and provision of information in preventing influenza cases requiring hospitalization

PREVENTIVE MEDICINE

卷:54

Article; Proceedings Paper

Godoy, Pere^1,2  Castilla, Jesus³  Delgado-Rodriguez, Miguel⁴  Martin, Vicente⁵  Alonso, Jordi⁶  Astray, Jenaro⁷  Canton, Rafael⁸  Gonzalez-Candelas, Fernando⁹  Maria Quintana, Jose¹⁰  Tamames, Sonia¹¹  Dominguez, Angela¹² 

[1] Generalitat Catalonia, Dept Salut, Catalonia, Spain

[2] Univ Lleida, Lleida, Spain

[3] Inst Salud Publ Navarra, Navarra, Spain

[4] Univ Jaen, Jaen, Spain

[5] Univ Leon, Inst Biomed, E-24071 Leon, Spain

[6] Inst Municipal Invest Med, E-08003 Barcelona, Spain

[7] Comunidad Madrid, Area Epidemiol, Madrid, Spain

[8] Hosp Univ Ramon Y Cajal, Madrid, Spain

[9] Univ Valencia, Ctr Super Invest Salud Publ, E-46003 Valencia, Spain

[10] Hosp Galdakao Usansolo, Unidad Invest, San Sebastian, Spain

[11] Junta Castilla & Leon, Consejeria Sanidad, Leon, Spain

[12] Univ Barcelona, E-08007 Barcelona, Spain

关键词: Influenza;    Non-pharmacological measures;    Hand hygiene;    Handwashing;    Transmission;    Hospitalization;    Prevention;    Case control study;    Epidemiology;   

DOI  :  10.1016/j.ypmed.2012.04.009

来源: Elsevier

【 摘 要 】

Background. The objective of the study was to investigate the effectiveness of non-pharmacological interventions in preventing cases of influenza requiring hospitalization. Methods. We performed a multicenter case-control study in 36 hospitals, in 2010 in Spain. Hospitalized influenza cases confirmed by reverse-transcription polymerase chain reaction and three matched controls (two hospital and one community control) per case Were selected. The use of non-pharmacological measures seven days before the onset of symptoms (frequency of hand washing, use of alcohol-based hand sanitizers and handwashing after touching contaminated surfaces) was collected. Results. We studied 813 cases hospitalized for influenza and 2274 controls. The frequency of hand washing 5-10 times (adjusted odds ratio [aOR] = 0.65) and >10 times (aOR = 0.59) and handwashing after contact with contaminated surfaces (aOR = 0.65) were protective factors and were dose-responsive (p < 0.001). Alcohol-based hand sanitizers were associated with marginal benefits (aOR = 0.82). Conclusions. Frequent handwashing should be recommended to prevent influenza cases requiring hospitalization. (C) 2012 Elsevier Inc. All rights reserved.

【 授权许可】

Free