Objective assessment of ADHD core symptoms in children with heavy prenatal alcohol exposure

PHYSIOLOGY & BEHAVIOR

卷:148

Article

Infante, M. Alejandra^1,2  Moore, Eileen M.¹  Nguyen, Tanya T.^1,2  Fourligas, Nikolaos³  Mattson, Sarah N.¹  Riley, Edward P.¹ 

[1] San Diego State Univ, Ctr Behav Teratol, Dept Psychol, San Diego, CA 92120 USA

[2] San Diego State Univ Calif San Diego Joint Doctor, San Diego, CA 92120 USA

[3] Pearson, Clin Assessment, Quotient ADHD Syst, Syst Engn, Westford, MA 01886 USA

关键词: Fetal;    Prenatal;    Alcohol;    Attention;    Activity;    Impulsivity;   

DOI  :  10.1016/j.physbeh.2014.10.014

来源: Elsevier

【 摘 要 】

Attention deficits are often observed in children with prenatal alcohol exposure and attention-deficit/hyperactivity disorder (ADHD) is commonly diagnosed in this population. This study used an objective assessment tool to examine differences between alcohol-exposed and non-exposed children on core symptoms of ADHD: inattention, impulsivity, and hyperactivity. Two groups of individuals, aged 7-14 years, participated in the study: alcohol-exposed children (AE, n = 43), and non-exposed children (CON, n = 54). Subjects were evaluated with the Quotient ADHD System, which provides objective data on ADHD core symptoms by combining an infrared motion tracking system and a computerized continuous performance task. Twelve separate ANCOVAs controlling for the effects of age and sex, were conducted on attention and motion variables. Results revealed that in comparison to the CON group, the AE group was significantly (p's < .05) less accurate, made an increased number of omission errors, had longer response latencies, and increased variability in response time. Moreover, the AE group spent less time staying still, and made an increased number of head movements, which traveled a larger distance, covered a greater area, and demonstrated a less complex movement pattern. No significant group differences were observed on the number of commission errors and temporal scaling. Our findings provide further support for the notion that inattention is a core deficit in children prenatally exposed to alcohol. Results from this study are also consistent with parent reports of increased hyperactivity. The Quotient ADHD System may be a useful objective measure of ADHD symptomatology in children with FASD. (C) 2014 Elsevier Inc. All rights reserved.

【 授权许可】

Free