Recent studies of the effects of sugars on brain systems involved in energy balance and reward: Relevance to low calorie sweeteners

PHYSIOLOGY & BEHAVIOR

卷:164

Article

Murray, Susan¹  Tulloch, Alastair¹  Criscitelli, Kristen¹  Avena, Nicole M.¹ 

[1] Icahn Sch Med Mt Sinai, Dept Pharmacol & Syst Therapeut, New York, NY 10025 USA

关键词: Sucrose;    Glucose;    Low calorie sweeteners;    Reward;    Dopamine;    Rats;   

DOI  :  10.1016/j.physbeh.2016.04.004

来源: Elsevier

【 摘 要 】

The alarmingly high rates of overweight and obesity pose a serious global health threat. Numerous factors can result in weight gain, one of which is excess consumption of caloric sweeteners. In an effort to aid weight loss efforts, many people have switched from caloric sweeteners to low calorie sweeteners, which provide sweet taste without the accompanying calories. In this review, we present an overview of the animal literature produced in the last 5 years highlighting the effects of sugar consumption on neural pathways involved in energy balance regulation and reward processing. We also examine the latest evidence that is beginning to elucidate the effects of low calorie sweeteners on these neural pathways, as well as how homeostatic and hedonic systems interact in response to, or to influence, sugar consumption. (C) 2016 Elsevier Inc. All rights reserved.

【 授权许可】

Free