Comparing the effect of daytime sleep and wakefulness on mnemonic discrimination

PHYSIOLOGY & BEHAVIOR

卷:224

Article

Cellini, Nicola^1,2,3,4  Mercurio, Marco¹  Vanzetti, Valentina¹  Bergamo, Damiana¹  Sarlo, Michela⁵ 

[1] Univ Padua, Dept Gen Psychol, Via Venezia 8, I-35131 Padua, Italy

[2] Univ Padua, Dept Biomed Sci, Via Ugo Bassi 58-B, I-35131 Padua, Italy

[3] Univ Padua, Padova Neurosci Ctr, Via Giuseppe Orus 2, I-35131 Padua, Italy

[4] Univ Padua, Human Inspired Technol Ctr, Via Luzzatti 4, I-35121 Padua, Italy

[5] Univ Urbino, Dept Commun Sci Humanities & Int Studies, Urbino Via Saffi 15, I-61029 Urbino, Italy

关键词: Hippocampus;    Memory consolidation;    Mnemonic discrimination;    Pattern separation;    Rest;    Sleep;   

DOI  :  10.1016/j.physbeh.2020.113078

来源: Elsevier

【 摘 要 】

Sleep is considered the optimal state to consolidate hippocampal-dependent memories. A particular memory process is mnemonic discrimination. Mnemonic discrimination refers to the ability to differentiate between novel and previously encountered information. Previous studies have found that mnemonic discrimination is impaired by sleep deprivation, whereas nocturnal sleep seems to protect memory representations when compared to a similar period of wakefulness. In this study we tested whether a daytime nap can facilitate mnemonic discrimination as assessed by the Mnemonic Similarity Task. Thirty-eight participants performed incidental learning of 256 images of unique everyday items at about 12:00 PM. Fifteen minutes later, in a recognition test, they were presented with 192 images: 64 targets (Old), 64 foils (New) and 64 lures (Similar to targets). For each image they had to decide whether it was already presented, never presented, or similar to an image presented during the encoding session. Then participants were split into a Nap group (N=19), who had a 90-min nap opportunity in the lab, and a Wake group (N=19), who stayed in the lab playing a low-arousing game. At 3:00 PM all participants performed a delayed recognition test, similar to the immediate test but with different images. Similar memory discrimination was observed in both the Nap and Wake group. The lack of a beneficial effect of sleep could be due to the differences between diurnal and nocturnal sleep and/or the potential role of video-games in facilitating memory discrimination during wakefulness.

【 授权许可】

Free