Chemosensory detectability of 1-butanol and 2-heptanone singly and in binary mixtures

PHYSIOLOGY & BEHAVIOR

卷:67

Article

Cometto-Muñiz, JE ; Cain, WS ; Abraham, MH ; Gola, JMR

关键词: olfaction;    chemosensory irritation;    odor;    nasal pungency;    eye irritation;    odor mixtures;    irritant mixtures;    anosmics;    1-butanol;    2-heptanone;    psychometric functions;   

DOI  :  10.1016/S0031-9384(99)00074-8

来源: Elsevier

【 摘 要 】

Using l-butanol and 2-heptanone as stimuli, we measured detectability (i.e., psychometric) functions for the odor, nasal pungency, and eye irritation of these two substances alone and in binary mixtures. Nasal pungency responses were tested in subjects lacking olfaction (i.e., anosmics) for whom odors do not interfere. Eye irritation responses were tested in normosmics and anosmics, and found to be similar in both groups so their results were pooled. When all stimuli-single and mixtures-were transformed into concentration units of one (or the other) chemical, a single function could fit all data from the same sensory end point with a correlation coefficient of 0.91 or higher. The outcome lends support, as a first approximation, to the notion of chemosensory agonism, in the sense of dose additivity, between the members of binary mixtures presented at perithreshold levels. (C) 1999 Elsevier Science Inc.

【 授权许可】

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