期刊论文详细信息
NEUROCOMPUTING 卷:318
Learning acoustic features to detect Parkinson's disease
Article
Wu, Kebin1  Zhang, David2  Lu, Guangming3  Guo, Zhenhua4 
[1] Tsinghua Univ, Elect Engn Dept, Beijing 100084, Peoples R China
[2] Chinese Univ Hong Kong Shenzhen, Sch Sci & Engn, Shenzhen 518055, Peoples R China
[3] Harbin Inst Technol Shenzhen, Shenzhen 518055, Peoples R China
[4] Tsinghua Univ, Grad Sch Shenzhen, Shenzhen 518055, Peoples R China
关键词: Feature learning;    Mel-spectrogram;    Parkinson's disease;    Spherical K-means;   
DOI  :  10.1016/j.neucom.2018.08.036
来源: Elsevier
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【 摘 要 】

Detecting Parkinson's disease (PD) based on voice analysis is meaningful due to its non-invasion and convenience. Traditional features adopted for PD detection are often hand-crafted, in which special expertise is needed. In this paper, we propose to employ feature learning technique to learn features automatically, where special expertise is unnecessary. First, calculate the first derivative of Mel-spectrogram with respect to time for pre-processed audio signals. Then, we use spherical K-means to train two dictionaries using samples of PD patients and healthy controls, respectively. Third, frames in an audio signal are encoded with the two dictionaries, followed by a pooling method to summarize over frames to obtain the learned features. Experiments show the superiority of the proposed method after comparison with two baseline algorithms. Additionally, issues like clustering number in spherical K-means and pooling method are discussed. Finally, by analyzing the similarities between the hand-crafted and learned features, some knowledge is obtained, which can guide future learning and design of features in PD detection. (C) 2018 Elsevier B.V. All rights reserved.

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