Emerging endocrine disruptors in two edible fish from the Persian Gulf: Occurrence, congener profile, and human health risk assessment

MARINE POLLUTION BULLETIN

卷:166

Article

Akhbarizadeh, Razegheh^1,2  Russo, Giacomo^3,4  Rossi, Sergio⁶  Golianova, Katarina⁷  Moore, Farid⁹  Guida, Marco⁸  De Falco, Maria⁸  Grumetto, Lucia^3,5 

[1] Bushehr Univ Med Sci, Syst Environm Hlth & Energy Res Ctr, Persian Gulf Biomed Sci Res Inst, Bushehr, Iran

[2] Bushehr Univ Med Sci, Persian Gulf Marine Biotechnol Res Ctr, Persian Gulf Biomed Sci Res Inst, Bushehr, Iran

[3] Univ Naples Federico II, Sch Med & Surg, Dept Pharm, Pharm Anal & Biopharm Lab, Via D Montesano 49, I-80131 Naples, Italy

[4] Edinburgh Napier Univ, Sch Appl Sci, Sighthill Campus,9 Sighthill Ct, Edinburgh EH11 4BN, Midlothian, Scotland

[5] Consorzio Interuniv INBB, Viale Medaglie Oro 305, I-00136 Rome, Italy

[6] CNR, Inst Genet & Biophys ABT, Via Pietro Castellino 111, I-80131 Naples, Italy

[7] Safarik Univ, Dept Biophys, Jesenna 5, Kosice 04154, Slovakia

[8] Univ Federico II Naples, Dept Biol, Naples, Italy

[9] Shiraz Univ, Coll Sci, Dept Earth Sci, Shiraz 71454, Iran

关键词: Endocrine disruptors;    Monte-Carlo simulation;    Fish;    Liver;    Muscle;    Persian gulf;   

DOI  :  10.1016/j.marpolbul.2021.112241

来源: Elsevier

【 摘 要 】

The occurrence of endocrine disrupting chemicals (EDCs) has been determined in two widely consumed fish species from Persian Gulf i.e., Epinephelus coioides and Platycephalus indicus by applying a validated analytical for the simultaneous detection of fourteen EDCs. The concentrations of all detected EDCs were greater in the liver than in the muscle (except for bisphenol A in P. indicus), suggesting a prolonged exposure of the fishes to these pollutants in the Persian Gulf. Specifically, the results showed that di (2-ethylhexyl) phthalate (DEHP) was the compound detected most frequently and at the highest concentration in both species. DEHP levels in ranged from 6.68 to 297.48 ?g g-dw? 1 and from 13.32 to 350.52 ?g g-dw? 1, in muscle and in liver, respectively. A risk assessment study was conducted, and demonstrated that consuming two fish based- meals per week may result in a moderate risk especially for vulnerable population groups.

【 授权许可】

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