Personality domains, duration of untreated psychosis, functioning, and symptom severity in first-episode psychosis

SCHIZOPHRENIA RESEARCH

卷:168

Article

Compton, Michael T.^1,2  Bakeman, Roger³  Alolayan, Yazeed⁴  Balducci, Pierfrancesco Maria^1,5  Bernardini, Francesco¹  Broussard, Beth¹  Crisafio, Anthony⁴  Cristofaro, Sarah⁶  Amar, Patrick⁶  Johnson, Stephanie⁶  Wan, Claire Ramsay⁷ 

[1] Lenox Hill Hosp, Dept Psychiat, New York, NY 10075 USA

[2] Hofstra Univ, Hofstra North Shore LIJ Sch Med, Dept Psychiat, Hempstead, NY 11550 USA

[3] Georgia State Univ, Dept Psychol, Atlanta, GA 30303 USA

[4] George Washington Univ, Sch Med & Hlth Sci, Dept Psychiat & Behav Sci, Washington, DC 20052 USA

[5] Univ Perugia, Scuola Specializzazione Psichiatria, I-06100 Perugia, Italy

[6] Emory Univ, Sch Med, Dept Psychiat & Behav Sci, Atlanta, GA USA

[7] Tufts Univ, Sch Med, Physician Assistant Program, Boston, MA 02111 USA

关键词: Duration of untreated psychosis;    First-episode psychosis;    Negative symptoms;    Personality;    Positive symptoms;    Psychosis;    Schizophrenia;   

DOI  :  10.1016/j.schres.2015.06.028

来源: Elsevier

【 摘 要 】

Objectives: Early-course psychotic disorders have been extensively studied in terms of phenomenology, but little is known about the influence of personality traits on clinical features of first-episode psychosis. The aim of this study was to explore how the big five personality domains (neuroticism, extraversion, openness, agreeableness, and conscientiousness) are associated with treatment delay (duration of untreated psychosis, DUP), functioning, and positive and negative symptom severity. Methods: Data for these analyses were obtained from 104 participants enrolled from psychiatric inpatient units in Atlanta, Georgia, between August 2008 and March 2011. The NEO Five-Factor Inventory (NEO-FFI) was used to assess personality domains, and all other variables were measured in a standardized and rigorous manner using psychometrically sound instruments. Correlational analyses and multiple linear regressions were carried out to examine the strength of associations between variables of interest. Results: Findings indicated that except for openness, all of the other personality variables contributed to some extent to the variance in DUP. Conscientiousness was positively correlated with functioning. Agreeableness was independently negatively associated with positive symptom severity and extraversion was independently negatively correlated with negative symptom severity. Conclusions: We report the first evidence suggesting that DUP is in part driven by personality domains. Functioning and symptom severity are also associated with those domains. Personality should be taken into account in order to better understand the phenomenology of early-course psychotic disorders as well as treatment-seeking behaviors. (C) 2015 Elsevier B.V. All rights reserved.

【 授权许可】

Free